Prostate Research Group

Prostate cancer is the most commonly diagnosed cancer among men and remains the second-leading cause of cancer death in men. The prostate-specific antigen (PSA) blood test disseminated 20 years ago and helped shift the disease stage at the time of diagnosis to a much lower and potentially more curable stage. However, PSA testing causes a lot of unnecessary biopsies and still misses clinically significant cancers.

Recently multi-parametric Magnetic resonance imaging (mpMRI) was shown to reduce unnecessary biopsies and decrease the number of missed cancers. Reading mpMRI is an expert skill. Our research focusses on exploring medical image analysis technology that can help improve mpMRI reading.

Another new development is a mpMRI-guided biopsy. To confirm the mpMRI diagnosis with a pathology analysis requires the ability to target mpMRI detected lesions. A cost-effective and convenient solution is to use transrectal ultrasound (TRUS). mpMRI guided TRUS biopsies are again an expert skill, mainly because relocating a lesion on ultrasound is difficult as the current technology for aligning mpMRI and TRUS is far from perfect. Our research focusses on exploring medical image analysis technology that can help improve biopsy.

The latest development is the ability of nano-MRI to detect lymph node metastasis. A reliable assessment of absence of positive lymph nodes has huge implications for survival and treatment options. Nano-MRI is a time-consuming task requiring expert reading skills. Our research focusses on exploring medical image analysis technology that can help improve nano-MRI reading.

Faculty

Researchers

Projects

Computer-aided detection of prostate cancer
Computer-aided detection of prostate cancer Prostate MRI has shown to be a great candidate for prostate cancer detection. Computer algorithms can condense all MRI information into images with high information content. More...
Computer-aided detection of metastatic pelvic lymph nodes
Computer-aided detection of metastatic pelvic lymph nodes The detection of nodal metastases is essential for prognosis and treatment choice in prostate cancer. Diagnosis can be improved using automation. More...
MR guided ultrasound prostate biopsy
MR guided ultrasound prostate biopsy Prostate biopsies are performed using systematic transrectal ultrasound (TRUS). MRI may be a better but more expensive modality. More...