A fully automatic unsupervised segmentation framework for the brain tissues in MR images

Q. Mahmood, A. Chodorowski, B. Ehteshami Bejnordi and M. Persson

in: Medical Imaging of Proceedings of the SPIE, 2014

DOI

Abstract

This paper presents a novel fully automatic unsupervised framework for the segmentation of brain tissues in magnetic resonance (MR) images. The framework is a combination of our proposed Bayesian-based adaptive mean shift (BAMS), a priori spatial tissue probability maps and fuzzy c-means. BAMS is applied to cluster the tissues in the joint spatialintensity feature space and then a fuzzy c-means algorithm is employed with initialization by a priori spatial tissue probability maps to assign the clusters into three tissue types; white matter (WM), gray matter (GM) and cerebrospinal fluid (CSF). The proposed framework is validated on multimodal synthetic as well as on real T1-weighted MR data with varying noise characteristics and spatial intensity inhomogeneity. The performance of the proposed framework is evaluated relative to our previous method BAMS and other existing adaptive mean shift framework. Both of these are based on the mode pruning and voxel weighted k-means algorithm for classifying the clusters into WM, GM and CSF tissue. The experimental results demonstrate the robustness of the proposed framework to noise and spatial intensity inhomogeneity, and that it exhibits a higher degree of segmentation accuracy in segmenting both synthetic and real MR data compared to competing methods.

A pdf file of this publication is available for personal use. Enter your e-mail address in the box below and press the button. You will receive an e-mail message with a link to the pdf file.