Publications of Ewoud Smit

2026

Papers in international journals

1. T. Perik, G. Litjens, N. Alves, E. Smit, M. Stommel, E. van Geenen, H. Huisman and J. Hermans, "Quantitative CT Perfusion as a prognostic biomarker for chemotherapy response in patients with pancreatic ductal adenocarcinoma", Abdominal Radiology, 2026.
   Abstract DOI

Preprints

1. M. Stegeman, L. Philipp, F. van der Graaf, M. D'Amato, C. Grisi, L. Builtjes, J.S. Bosma, J. Lefkes, R. Weber, J. Meakin, T. Koopman, A. Mickan, M. Prokop, E. Smit, G. Litjens, J. van der Laak, B. van Ginneken, M. de Rooij, H. Huisman, C. Jacobs, F. Ciompi and A. Hering, "Designing UNICORN: a Unified Benchmark for Imaging in Computational Pathology, Radiology, and Natural Language", arXiv:2603.02790, 2026.
   Abstract DOI arXiv

Papers in conference proceedings

1. J. Tagscherer, S. de Boer, L. Philipp, F. van der Graaf, D. Peeters, J. Bosma, L. Leijten, B. Obreja, E. Smit and A. Hering, "EvalBlocks: A Modular Pipeline for Rapidly Evaluating Foundation Models in Medical Imaging", 2026.
   arXiv
2. R. Weber, N. Rocholl, M. de Grauw, M. Prokop, E. Smit and A. Hering, "ULS+: Data-driven Model Adaptation Enhances Lesion Segmentation", 2026.
   arXiv

2025

Preprints

1. X. Pham, G. Vuurberg, M. Doppen, J. Roosen, T. Stille, T. Ha, T. Quach, Q. Dang, M. Luu, E. Smit, H. Mai, M. Heinrich, B. van Ginneken, M. Prokop and A. Hering, "TotalRegistrator: Towards a Lightweight Foundation Model for CT Image Registration", arXiv:2508.04450, 2025.
   Abstract DOI arXiv
2. N. Rocholl, E. Smit, M. Prokop and A. Hering, "Unstable Prompts, Unreliable Segmentations: A Challenge for Longitudinal Lesion Analysis", arXiv:2507.19230, 2025.
   Abstract DOI arXiv

2024

Preprints

1. M. de Grauw, E. Scholten, E. Smit, M. Rutten, M. Prokop, B. van Ginneken and A. Hering, "The ULS23 Challenge: a Baseline Model and Benchmark Dataset for 3D Universal Lesion Segmentation in Computed Tomography", arXiv:2406.05231, 2024.
   Abstract DOI PMID arXiv

2022

Abstracts

1. M. Grauw, B. Ginneken, B. Geisler, E. Smit, M. Rooij, S. Schalekamp and M. Prokop, "Deep learning universal lesion segmentation for automated RECIST measurements on CT: comparison to manual assessment by radiologists", European Congress of Radiology, 2022.
   Abstract

2021

Papers in international journals

1. T. Perik, E. van Genugten, E. Aarntzen, E. Smit, H. Huisman and J. Hermans, "Quantitative CT perfusion imaging in patients with pancreatic cancer: a systematic review", Abdominal Radiology, 2021.
   Abstract DOI Cited by ~9

2019

Papers in international journals

1. D. Grob, E. Smit, J. Prince, J. Kist, L. Stöger, B. Geurts, M. Snoeren, R. van Dijk, L. Oostveen, M. Prokop, C. Schaefer-Prokop, I. Sechopoulos and M. Brink, "Iodine Maps from Subtraction CT or Dual-Energy CT to Detect Pulmonary Emboli with CT Angiography: A Multiple-Observer Study", Radiology, 2019;292:197-205.
   DOI PMID Cited by ~37
2. D. Grob, E. Smit, L. Oostveen, M. Snoeren, M. Prokop, C. Schaefer-Prokop, I. Sechopoulos and M. Brink, "Image Quality of Iodine Maps for Pulmonary Embolism: A Comparison of Subtraction CT and Dual-Energy CT", American Journal of Roentgenology, 2019;212:1253-1259.
   DOI PMID Cited by ~8

PhD theses

1. E. Smit, "Feasibility of a single-acquisition CT stroke protocol", PhD thesis, 2019.
   Abstract

2018

Papers in international journals

1. M. Oei, F. Meijer, J. Mordang, E. Smit, A. Idema, B. Goraj, H. Laue, M. Prokop and R. Manniesing, "Observer Variability of Reference Tissue Selection for Relative Cerebral Blood Volume Measurements in Glioma Patients", European Radiology, 2018;28(9):3902-3911.
   Abstract DOI PMID Cited by ~11

2017

Papers in international journals

1. R. Manniesing, M. Oei, L. Oostveen, J. Melendez, E. Smit, B. Platel, C. Sánchez, F. Meijer, M. Prokop and B. van Ginneken, "White Matter and Gray Matter Segmentation in 4D Computed Tomography", Scientific Reports, 2017;7(119).
   Abstract DOI PMID Cited by ~24
2. M. Oei, F. Meijer, W. van der Woude, E. Smit, B. van Ginneken, M. Prokop and R. Manniesing, "Interleaving cerebral CT perfusion with neck CT angiography part I. Proof of concept and accuracy of cerebral perfusion values", European Radiology, 2017;27(6):2649-2656.
   Abstract DOI PMID Cited by ~8
3. M. Oei, F. Meijer, W. van der Woude, E. Smit, B. van Ginneken, R. Manniesing and M. Prokop, "Interleaving cerebral CT perfusion with neck CT angiography. Part II: clinical implementation and image quality", European Radiology, 2017;27(6):2411-2418.
   Abstract DOI PMID Cited by ~11

2016

Abstracts

1. R. Becks, M. Meijs, R. Manniesing, J. Vister, S. Schalekamp, R. Mann, S. Steens, E. Smit, E. van Dijk, M. Prokop and F. Meijer, "Additional Value of Brain CT Perfusion in The Detection of Intracranial Vessel Occlusion in Acute Ischemic Stroke: A (Multi Experience Level) Inter-Observer Study", Annual Meeting of the Radiological Society of North America, 2016.
   Abstract

2015

Papers in international journals

1. E. Smit, E. Vonken, F. Meijer, J. Dankbaar, A. Horsch, B. van Ginneken, B. Velthuis, I. van der Schaaf and M. Prokop, "Timing-Invariant CT Angiography Derived from CT Perfusion Imaging in Acute Stroke: A Diagnostic Performance Study", American Journal of Neuroradiology, 2015;36:1834-1838.
   Abstract DOI PMID Cited by ~22
2. H. Kortman, E. Smit, M. Oei, R. Manniesing, M. Prokop and F. Meijer, "4D-CTA in Neurovascular Disease: A Review", American Journal of Neuroradiology, 2015;36(6):1026-1033.
   Abstract DOI PMID Cited by ~77

2014

Papers in international journals

1. R. van den Boom, R. Manniesing, M. Oei, W. van der Woude, E. Smit, H. Laue, B. van Ginneken and M. Prokop, "A 4D Digital Phantom for Patient-Specific Simulation of Brain CT Perfusion Protocols", Medical Physics, 2014;41:071907-1 - 071907-9.
   Abstract DOI PMID Download Cited by ~6

2013

Papers in international journals

1. E. Smit, E. Vonken, T. van Seeters, J. Dankbaar, I. van der Schaaf, L. Kappelle, B. van Ginneken, B. Velthuis and M. Prokop, "Timing-Invariant Imaging of Collateral Vessels in Acute Ischemic Stroke", Stroke, 2013;44:2194-2199.
   Abstract DOI PMID Download Cited by ~97

Papers in conference proceedings

1. J. Mordang, M. Oei, R. van den Boom, E. Smit, M. Prokop, B. van Ginneken and R. Manniesing, "A Pattern Recognition Framework for Vessel Segmentation in 4D CT of the Brain", Medical Imaging, 2013:866919.
   Abstract DOI Cited by ~1
2. J. Charbonnier, E. Smit, M. Viergever, B. Velthuis and P. Vos, "Computer-aided diagnosis of acute ischemic stroke based on cerebral hypoperfusion using 4D CT angiography", Medical Imaging, 2013;8670.
   Abstract DOI

2012

Papers in international journals

1. A. Mendrik, E. Vonken, G. de Kort, B. van Ginneken, E. Smit, M. Viergever and M. Prokop, "Improved Arterial Visualization in Cerebral CT Perfusion-Derived Arteriograms Compared with Standard CT Angiography: A Visual Assessment Study", American Journal of Neuroradiology, 2012;33(11):2171-2177.
   Abstract DOI PMID Download Cited by ~11
2. E. Smit, E. Vonken, I. van der Schaaf, A. Mendrik, J. Dankbaar, A. Horsch, T. van Seeters, B. van Ginneken and M. Prokop, "Timing-Invariant Reconstruction for Deriving High-quality CT Angiographic Data from Cerebral CT Perfusion Data", Radiology, 2012;263:216-225.
   Abstract DOI PMID Download Cited by ~66

Abstracts

1. M. Oei, R. van den Boom, L. Oostveen, S. Lafebre, E. Smit, B. van Ginneken, R. Manniesing and M. Prokop, "Hybrid digital phantom for optimizing data acquisition strategies in CT perfusion", European Congress of Radiology, 2012.
   Abstract
2. E. Smit, E. Vonken, F. Meijer, J. Dankbaar, A. Horsch, B. van Ginneken, B. Velthuis, I. van der Schaaf and M. Prokop, "Acute Ischemic Stroke Assessment on CT-Angiography That Derived from CT-Perfusion Images", Annual Meeting of the Radiological Society of North America, 2012.
   Abstract

2011

Papers in international journals

1. A. Mendrik, E. Vonken, B. van Ginneken, H. de Jong, A. Riordan, T. van Seeters, E. Smit, M. Viergever and M. Prokop, "TIPS bilateral noise reduction in 4D CT perfusion scans produces high-quality cerebral blood flow maps", Physics in Medicine and Biology, 2011;56:3857-3872.
   Abstract DOI PMID Download Cited by ~84

2010

Papers in international journals

1. A. Mendrik, E. Vonken, B. van Ginneken, E. Smit, A. Waaijer, G. Bertolini, M. Viergever and M. Prokop, "Automatic segmentation of intracranial arteries and veins in four-dimensional cerebral CT perfusion scans", Medical Physics, 2010;37(6):2956-2966.
   Abstract DOI PMID Download Cited by ~38

Papers in conference proceedings

1. E. Smit, J. Dankbaar, A. Mendrik, B. van Ginneken, E. Vonken and M. Prokop, "Reconstruction of High Quality CT Angiography from Noisy Cerebral CT Perfusion Data", Annual Meeting of the Radiological Society of North America, 2010.
   Abstract

2009

Papers in conference proceedings

1. A. Mendrik, E. Vonken, A. Waaijer, E. Smit, M. Prokop and B. van Ginneken, "Segmentation of arteries and veins on 4D CT perfusion scans for constructing arteriograms and venograms", Medical Imaging, 2009;7259:72590Z1-72590Z7.
   Abstract DOI Cited by ~1

Abstracts

1. E. Smit, A. Mendrik, A. Waaijer, G. Bertolini, E. Vonken, B. van Ginneken and M. Prokop, "Reconstruction of high-quality CTA from noisy cerebral CT perfusion data", European Congress of Radiology, 2009.
   Abstract
2. A. Mendrik, E. Vonken, E. Smit, B. van Ginneken and M. Prokop, "Reduction of Venous Overprojection Using Cerebral Arteriograms from CT Perfusion Scans of Subarachnoid Hemorrhage Patients", Annual Meeting of the Radiological Society of North America, 2009.