Pathology

A large part of DIAG focuses on the analysis of pathology images and is embedded in the Department of Pathology of Radboudumc and has a strong translational focus. The history of the group reaches back to the early 1980s, and in 2013 the group joined DIAG and started to grow rapidly, facilitated by the simultaneous advents of digital pathology and deep learning.

Projects focus on two areas:

  1. increasing efficiency of the current pathology diagnostic process by developing and validating computer aided diagnosis (CAD) workflows;
  2. supporting personalized medicine by developing image based biomarkers that are predictive for patient outcome or therapy response. The latter may be based either on H&E stained tissue sections or immunohistochemistry.

Below you will find an overview of current research projects. More details can be found on the Computational Pathology Group's own site.

Projects

AIRAT: Artificial Intelligence for reproducible analysis of tumor proliferation

The AIRAT project aims to validate and implement AI for mitosis counting in routine pathology practice.

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BIGPICTURE

The goal of Bigpicture is to accelerate the development of AI in pathology by providing a large repository of high-quality annotated pathology data, accessible in a responsible, inclusive and sustainable way.

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COMMITMENT

The aim of COMMITMENT is to develop and validate deep learning methods for improving breast cancer treatment decision-making.

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DALPHIN

The aim of DALPHIN is to develop a multicentric open benchmark for digital pathology assistants.

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Deep Derma

The aim of this project is to apply artificial intelligence to detect basal cell carcinoma.

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DIAGGRAFT

Investigation of AI for kidney transplant pathology.

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IGNITE

The goal of IGNITE is to use automatic biomarker extraction with deep learning to predict the response of non-small cell lung cancer patients to immunotherapy.

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PANCAIM

Investigation of AI for pancreatic cancer in radiology, pathology, genomics.

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PathRad Fusion

The aim of this project is to integrate histopathological and radiological images to improve our understanding of disease diagnosis and progression in prostate cancer.

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UNIC

The aim of UNIC is to develop artificial intelligence methods to refine diffuse-type gastric cancer (DGC) diagnostics.

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